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Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice

Hepatic encephalopathy (HE) is a neuropsychiatric complication that occurs due to deteriorating hepatic function and this syndrome influences patient quality of life, clinical management strategies and survival. During acute liver failure, circulating bile acids increase due to a disruption of the e...

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Detalles Bibliográficos
Autores principales: McMillin, Matthew, Frampton, Gabriel, Grant, Stephanie, Khan, Shamyal, Diocares, Juan, Petrescu, Anca, Wyatt, Amy, Kain, Jessica, Jefferson, Brandi, DeMorrow, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496949/
https://www.ncbi.nlm.nih.gov/pubmed/28725183
http://dx.doi.org/10.3389/fncel.2017.00191