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Angiotensin‐(1–7) protects cardiomyocytes against high glucose‐induced injuries through inhibiting reactive oxygen species‐activated leptin–p38 mitogen‐activated protein kinase/extracellular signal‐regulated protein kinase 1/2 pathways, but not the leptin–c‐Jun N‐terminal kinase pathway in vitro

AIMS/INTRODUCTION: Angiotensin‐(1–7) (Ang‐[1–7]), recognized as a new bioactive peptide in the renin–angiotensin system, shows biological and pharmacological properties in diabetic cardiovascular diseases. The leptin‐induced p38 mitogen‐activated protein kinase (MAPK) pathway has been reported to co...

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Detalles Bibliográficos
Autores principales: Lei, Yiyan, Xu, Qing, Zeng, Bo, Zhang, Wei, Zhen, Yulan, Zhai, Yuansheng, Cheng, Fei, Mei, Weiyi, Zheng, Dongdan, Feng, Jianqiang, Lan, Jun, Chen, Jingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497033/
https://www.ncbi.nlm.nih.gov/pubmed/27896943
http://dx.doi.org/10.1111/jdi.12603