Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Clinical challenges exist in reducing prostate cancer (PCa) disparities. The RNA splicing landscape of PCa across racial populations has not been fully explored as a potential molecular mechanism contributing to race-related tumour aggressiveness. Here, we identify novel genome-wide, race-specific R...

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Detalles Bibliográficos
Autores principales: Wang, Bi-Dar, Ceniccola, Kristin, Hwang, SuJin, Andrawis, Ramez, Horvath, Anelia, Freedman, Jennifer A., Olender, Jacqueline, Knapp, Stefan, Ching, Travers, Garmire, Lana, Patel, Vyomesh, Garcia-Blanco, Mariano A., Patierno, Steven R., Lee, Norman H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497057/
https://www.ncbi.nlm.nih.gov/pubmed/28665395
http://dx.doi.org/10.1038/ncomms15921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497057/
https://www.ncbi.nlm.nih.gov/pubmed/28665395
http://dx.doi.org/10.1038/ncomms15921

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