GroEL actively stimulates folding of the endogenous substrate protein PepQ

Many essential proteins cannot fold without help from chaperonins, like the GroELS system of Escherichia coli. How chaperonins accelerate protein folding remains controversial. Here we test key predictions of both passive and active models of GroELS-stimulated folding, using the endogenous E. coli m...

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Detalles Bibliográficos
Autores principales: Weaver, Jeremy, Jiang, Mengqiu, Roth, Andrew, Puchalla, Jason, Zhang, Junjie, Rye, Hays S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497066/
https://www.ncbi.nlm.nih.gov/pubmed/28665408
http://dx.doi.org/10.1038/ncomms15934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497066/
https://www.ncbi.nlm.nih.gov/pubmed/28665408
http://dx.doi.org/10.1038/ncomms15934

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