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GroEL actively stimulates folding of the endogenous substrate protein PepQ
Many essential proteins cannot fold without help from chaperonins, like the GroELS system of Escherichia coli. How chaperonins accelerate protein folding remains controversial. Here we test key predictions of both passive and active models of GroELS-stimulated folding, using the endogenous E. coli m...
Autores principales: | Weaver, Jeremy, Jiang, Mengqiu, Roth, Andrew, Puchalla, Jason, Zhang, Junjie, Rye, Hays S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497066/ https://www.ncbi.nlm.nih.gov/pubmed/28665408 http://dx.doi.org/10.1038/ncomms15934 |
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