Cargando…

Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer

BACKGROUND: Methionyl-tRNA synthetase (MRS) plays a critical role in initiating translation by transferring Met to the initiator tRNA (tRNA(i) (Met)) and protection against ROS-mediated damage, suggesting that its overexpression is related to cancer growth and drug resistance. In this study, the cli...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun Young, Jung, Ji Ye, Kim, Arum, Kim, Kwangsoo, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497355/
https://www.ncbi.nlm.nih.gov/pubmed/28679377
http://dx.doi.org/10.1186/s12885-017-3452-9