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Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer
BACKGROUND: Methionyl-tRNA synthetase (MRS) plays a critical role in initiating translation by transferring Met to the initiator tRNA (tRNA(i) (Met)) and protection against ROS-mediated damage, suggesting that its overexpression is related to cancer growth and drug resistance. In this study, the cli...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497355/ https://www.ncbi.nlm.nih.gov/pubmed/28679377 http://dx.doi.org/10.1186/s12885-017-3452-9 |