Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species

Stem cells have been assumed to demonstrate a reliance on anaerobic energy generation, suited to their hypoxic in vivo environment. However, we found that human mesenchymal stem cells (hMSCs) have an active oxidative metabolism with a range of substrates. More ATP was consistently produced from subs...

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Detalles Bibliográficos
Autores principales: Board, Mary, Lopez, Colleen, van den Bos, Christian, Callaghan, Richard, Clarke, Kieran, Carr, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497396/
https://www.ncbi.nlm.nih.gov/pubmed/28483672
http://dx.doi.org/10.1016/j.biocel.2017.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497396/
https://www.ncbi.nlm.nih.gov/pubmed/28483672
http://dx.doi.org/10.1016/j.biocel.2017.05.007

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