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New insights into SMA pathogenesis: immune dysfunction and neuroinflammation

Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by motor neuron degeneration, although defects in multiple cell types and tissues have also been implicated. Three independent laboratories recently identified immune organ defects in SMA. We therefore propose a novel pathogenic...

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Detalles Bibliográficos
Autores principales: Deguise, Marc‐Olivier, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497530/
https://www.ncbi.nlm.nih.gov/pubmed/28695153
http://dx.doi.org/10.1002/acn3.423