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Dysregulation of 14‐3‐3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology

OBJECTIVE: The highly conserved 14‐3‐3 proteins interact with key players involved in Parkinson's disease (PD) and other neurodegenerative disorders. We recently demonstrated that 14‐3‐3 phosphorylation is increased in PD models and that increased 14‐3‐3 phosphorylation reduces the neuroprotect...

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Detalles Bibliográficos
Autores principales: McFerrin, Michael B., Chi, Xiaofei, Cutter, Gary, Yacoubian, Talene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497531/
https://www.ncbi.nlm.nih.gov/pubmed/28695147
http://dx.doi.org/10.1002/acn3.421