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Suberoylanilide hydroxamic acid sensitizes neuroblastoma to paclitaxel by inhibiting thioredoxin‐related protein 14‐mediated autophagy

Paclitaxel is not as effective for neuroblastoma as most of the front‐line chemotherapeutics due to drug resistance. This study explored the regulatory mechanism of paclitaxel‐associated autophagy and potential solutions to paclitaxel resistance in neuroblastoma. The formation of autophagic vesicles...

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Detalles Bibliográficos
Autores principales: Zhen, Zijun, Yang, Kaibin, Ye, Litong, You, Zhiyao, Chen, Rirong, Liu, Ying, He, Youjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497723/
https://www.ncbi.nlm.nih.gov/pubmed/28498513
http://dx.doi.org/10.1111/cas.13279