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Antitumor activity and pharmacologic characterization of the depsipeptide analog as a novel histone deacetylase/ phosphatidylinositol 3‐kinase dual inhibitor
Histone deacetylase (HDAC)/phosphatidylinositol 3‐kinase (PI3K) dual inhibition is a promising strategy for the treatment of intractable cancers because of the advantages of overcoming potential resistance and showing synergistic effects. Therefore, development of an HDAC/PI3K dual inhibitor is reas...
Autores principales: | Saijo, Ken, Imai, Hiroo, Chikamatsu, Sonoko, Narita, Koichi, Katoh, Tadashi, Ishioka, Chikashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497724/ https://www.ncbi.nlm.nih.gov/pubmed/28406576 http://dx.doi.org/10.1111/cas.13255 |
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