Antitumor activity and pharmacologic characterization of the depsipeptide analog as a novel histone deacetylase/ phosphatidylinositol 3‐kinase dual inhibitor

Histone deacetylase (HDAC)/phosphatidylinositol 3‐kinase (PI3K) dual inhibition is a promising strategy for the treatment of intractable cancers because of the advantages of overcoming potential resistance and showing synergistic effects. Therefore, development of an HDAC/PI3K dual inhibitor is reas...

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Detalles Bibliográficos
Autores principales: Saijo, Ken, Imai, Hiroo, Chikamatsu, Sonoko, Narita, Koichi, Katoh, Tadashi, Ishioka, Chikashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497724/
https://www.ncbi.nlm.nih.gov/pubmed/28406576
http://dx.doi.org/10.1111/cas.13255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497724/
https://www.ncbi.nlm.nih.gov/pubmed/28406576
http://dx.doi.org/10.1111/cas.13255

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