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Glucose metabolism‐targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor‐induced drug‐tolerant persisters

In pathway‐targeted cancer drug therapies, the relatively rapid emergence of drug‐tolerant persisters (DTPs) substantially limits the overall therapeutic benefit. However, little is known about the roles of DTPs in drug resistance. In this study, we investigated the features of epidermal growth fact...

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Detalles Bibliográficos
Autores principales: Kunimasa, Kei, Nagano, Tatsuya, Shimono, Yohei, Dokuni, Ryota, Kiriu, Tatsunori, Tokunaga, Shuntaro, Tamura, Daisuke, Yamamoto, Masatsugu, Tachihara, Motoko, Kobayashi, Kazuyuki, Satouchi, Miyako, Nishimura, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497794/
https://www.ncbi.nlm.nih.gov/pubmed/28445002
http://dx.doi.org/10.1111/cas.13266