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Roles of the PDZ‐binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

The high‐risk human papillomavirus E6 proteins have been shown to interact with and lead to degradation of PDZ‐domain‐containing proteins through its carboxy‐terminal motif. This PDZ‐binding motif plays important roles in transformation of cultured cells and carcinogenesis of E6‐transgenic mice. How...

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Detalles Bibliográficos
Autores principales: Yoshimatsu, Yuki, Nakahara, Tomomi, Tanaka, Katsuyuki, Inagawa, Yuki, Narisawa‐Saito, Mako, Yugawa, Takashi, Ohno, Shin‐ichi, Fujita, Masatoshi, Nakagama, Hitoshi, Kiyono, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497797/
https://www.ncbi.nlm.nih.gov/pubmed/28440909
http://dx.doi.org/10.1111/cas.13264