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Antitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivo

Focal adhesion kinase (FAK) overexpression is related to invasive and metastatic properties in different kinds of cancers. Target therapy by inhibiting FAK has achieved promising effect in some cancer treatments, but its effect in human osteosarcoma has not been well studied. In the present study, w...

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Detalles Bibliográficos
Autores principales: Hu, Chuanzhen, Chen, Xu, Wen, Junxiang, Gong, Liangzhi, Liu, Zhuochao, Wang, Jun, Liang, Jing, Hu, Fangqiong, Zhou, Qi, Wei, Li, Shen, Yuhui, Zhang, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497929/
https://www.ncbi.nlm.nih.gov/pubmed/28406574
http://dx.doi.org/10.1111/cas.13256