Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle

The pathogenesis of diabetes-associated motility disorders are multifactorial and attributed to abnormalities in extrinsic and intrinsic innervation, and a decrease in the number of interstitial cells of Cajal, and nNOS expression and activity. Here we studied the effect of hyperglycemia on smooth m...

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Detalles Bibliográficos
Autores principales: Mahavadi, Sunila, Sriwai, Wimolpak, Manion, Olivia, Grider, John R., Murthy, Karnam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497948/
https://www.ncbi.nlm.nih.gov/pubmed/28678840
http://dx.doi.org/10.1371/journal.pone.0178574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497948/
https://www.ncbi.nlm.nih.gov/pubmed/28678840
http://dx.doi.org/10.1371/journal.pone.0178574

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