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Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle
The pathogenesis of diabetes-associated motility disorders are multifactorial and attributed to abnormalities in extrinsic and intrinsic innervation, and a decrease in the number of interstitial cells of Cajal, and nNOS expression and activity. Here we studied the effect of hyperglycemia on smooth m...
Autores principales: | Mahavadi, Sunila, Sriwai, Wimolpak, Manion, Olivia, Grider, John R., Murthy, Karnam S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497948/ https://www.ncbi.nlm.nih.gov/pubmed/28678840 http://dx.doi.org/10.1371/journal.pone.0178574 |
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