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Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases

BACKGROUND: Since leprosy is both treated and controlled by multidrug therapy (MDT) it is important to monitor recurrent cases for drug resistance and to distinguish between relapse and reinfection as a means of assessing therapeutic efficacy. All three objectives can be reached with single nucleoti...

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Detalles Bibliográficos
Autores principales: Stefani, Mariane M. A., Avanzi, Charlotte, Bührer-Sékula, Samira, Benjak, Andrej, Loiseau, Chloé, Singh, Pushpendra, Pontes, Maria A. A., Gonçalves, Heitor S., Hungria, Emerith M., Busso, Philippe, Piton, Jérémie, Silveira, Maria I. S., Cruz, Rossilene, Schetinni, Antônio, Costa, Maurício B., Virmond, Marcos C. L., Diorio, Suzana M., Dias-Baptista, Ida M. F., Rosa, Patricia S., Matsuoka, Masanori, Penna, Maria L. F., Cole, Stewart T., Penna, Gerson O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498066/
https://www.ncbi.nlm.nih.gov/pubmed/28617800
http://dx.doi.org/10.1371/journal.pntd.0005598