SOX2 regulates acinar cell development in the salivary gland

Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gland, we demonstrate an unexpected role for SOX2 and...

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Detalles Bibliográficos
Autores principales: Emmerson, Elaine, May, Alison J, Nathan, Sara, Cruz-Pacheco, Noel, Lizama, Carlos O, Maliskova, Lenka, Zovein, Ann C, Shen, Yin, Muench, Marcus O, Knox, Sarah M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498133/
https://www.ncbi.nlm.nih.gov/pubmed/28623666
http://dx.doi.org/10.7554/eLife.26620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498133/
https://www.ncbi.nlm.nih.gov/pubmed/28623666
http://dx.doi.org/10.7554/eLife.26620

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