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Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer

Advances in the understanding of the Hippo signaling as a key regulatory pathway of proliferation and apoptosis have provided mechanical insights for controlling organ size and tumorigenicity. Recently, much attention has been directed to the regulation of LATS1/2 (large tumor suppressor) kinases th...

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Detalles Bibliográficos
Autores principales: Kim, Youngeun, Jho, Eek-hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498137/
https://www.ncbi.nlm.nih.gov/pubmed/28502290
http://dx.doi.org/10.5483/BMBRep.2017.50.6.078