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Chronophin activation is necessary in Doxorubicin-induced actin cytoskeleton alteration

Although doxorubicin (Dox)-induced oxidative stress is known to be associated with cytotoxicity, the precise mechanism remains unclear. Genotoxic stress not only generates free radicals, but also affects actin cytoskeleton stability. We showed that Dox-induced RhoA signaling stimulated actin cytoske...

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Detalles Bibliográficos
Autores principales: Lee, Su Jin, Park, Jeen Woo, Kang, Beom Sik, Lee, Dong-Seok, Lee, Hyun-Shik, Choi, Sooyoung, Kwon, Oh-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498145/
https://www.ncbi.nlm.nih.gov/pubmed/28502289
http://dx.doi.org/10.5483/BMBRep.2017.50.6.061