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Chronophin activation is necessary in Doxorubicin-induced actin cytoskeleton alteration
Although doxorubicin (Dox)-induced oxidative stress is known to be associated with cytotoxicity, the precise mechanism remains unclear. Genotoxic stress not only generates free radicals, but also affects actin cytoskeleton stability. We showed that Dox-induced RhoA signaling stimulated actin cytoske...
Autores principales: | Lee, Su Jin, Park, Jeen Woo, Kang, Beom Sik, Lee, Dong-Seok, Lee, Hyun-Shik, Choi, Sooyoung, Kwon, Oh-Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498145/ https://www.ncbi.nlm.nih.gov/pubmed/28502289 http://dx.doi.org/10.5483/BMBRep.2017.50.6.061 |
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