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Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes

Reversible post-translational modifications of various cardiac proteins regulate the mechanical properties of the cardiomyocytes and thus modulate the contractile performance of the heart. The giant protein titin forms a continuous filament network in the sarcomeres of striated muscle cells, where i...

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Detalles Bibliográficos
Autores principales: Hamdani, Nazha, Herwig, Melissa, Linke, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498327/
https://www.ncbi.nlm.nih.gov/pubmed/28510118
http://dx.doi.org/10.1007/s12551-017-0263-9