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Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes
Reversible post-translational modifications of various cardiac proteins regulate the mechanical properties of the cardiomyocytes and thus modulate the contractile performance of the heart. The giant protein titin forms a continuous filament network in the sarcomeres of striated muscle cells, where i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498327/ https://www.ncbi.nlm.nih.gov/pubmed/28510118 http://dx.doi.org/10.1007/s12551-017-0263-9 |