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Administration of Tauroursodeoxycholic Acid Attenuates Early Brain Injury via Akt Pathway Activation

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays an important role in the pathophysiology of TBI. Tauroursodeoxycholic acid (TUDCA), a hydrophilic bile acid, has been rep...

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Detalles Bibliográficos
Autores principales: Sun, Dongdong, Gu, Gang, Wang, Jianhao, Chai, Yan, Fan, Yueshan, Yang, Mengchen, Xu, Xin, Gao, Weiwei, Li, Fei, Yin, Dongpei, Zhou, Shuai, Chen, Xin, Zhang, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498474/
https://www.ncbi.nlm.nih.gov/pubmed/28729823
http://dx.doi.org/10.3389/fncel.2017.00193