Cargando…

Administration of Tauroursodeoxycholic Acid Attenuates Early Brain Injury via Akt Pathway Activation

Traumatic brain injury (TBI) is one of the leading causes of trauma-induced mortality and disability, and emerging studies have shown that endoplasmic reticulum (ER) stress plays an important role in the pathophysiology of TBI. Tauroursodeoxycholic acid (TUDCA), a hydrophilic bile acid, has been rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Dongdong, Gu, Gang, Wang, Jianhao, Chai, Yan, Fan, Yueshan, Yang, Mengchen, Xu, Xin, Gao, Weiwei, Li, Fei, Yin, Dongpei, Zhou, Shuai, Chen, Xin, Zhang, Jianning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498474/ https://www.ncbi.nlm.nih.gov/pubmed/28729823 http://dx.doi.org/10.3389/fncel.2017.00193

Ejemplares similares

IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury
por: Gao, Weiwei, et al.
Publicado: (2017)

Semaphorin 3A Contributes to Secondary Blood–Brain Barrier Damage After Traumatic Brain Injury
por: Yang, Mengchen, et al.
Publicado: (2019)

Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury
por: Guo, Honglei, et al.
Publicado: (2016)

Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury
por: Xu, Xin, et al.
Publicado: (2017)

Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes
por: Zhang, Jing, et al.
Publicado: (2016)

Tauroursodeoxycholic acid reduces ER stress by regulating of Akt-dependent cellular prion protein
por: Yoon, Yeo Min, et al.
Publicado: (2016)

Mechanisms of tauroursodeoxycholate-mediated inhibition of apoptosis
por: Sommerfeld, Annika, et al.
Publicado: (2014)

Preparation and toxicity evaluation of a novel nattokinase-tauroursodeoxycholate complex
por: Feng, Rui, et al.
Publicado: (2018)

Tauroursodeoxycholic acid attenuates endoplasmic reticulum stress and protects the liver from chronic intermittent hypoxia induced injury
por: Hou, Yanpeng, et al.
Publicado: (2017)

Therapeutic Potential of Tauroursodeoxycholic Acid for the Treatment of Osteoporosis
por: Ahn, Tae-Keun, et al.
Publicado: (2020)

Tauroursodeoxycholic acid (TUDCA) attenuates pressure overload-induced cardiac remodeling by reducing endoplasmic reticulum stress
por: Rani, Shilpa, et al.
Publicado: (2017)

Tauroursodeoxycholic acid mediates endoplasmic reticulum stress and autophagy in adrenocortical carcinoma cells
por: Huang, Xuemei, et al.
Publicado: (2019)

Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis
por: Elia, A. E., et al.
Publicado: (2015)

Tauroursodeoxycholic Acid Enhances Osteogenic Differentiation through EGFR/p-Akt/CREB1 Pathway in Mesenchymal Stem Cells
por: Kang, Hyojin, et al.
Publicado: (2023)

Prevention of Acute Kidney Injury by Tauroursodeoxycholic Acid in Rat and Cell Culture Models
por: Gupta, Sandeep, et al.
Publicado: (2012)

Tauroursodeoxycholic acid enhances the development of porcine embryos derived from in vitro-matured oocytes and evaporatively dried spermatozoa
por: Li, Xiao-Xia, et al.
Publicado: (2017)

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases
por: Khalaf, Kareem, et al.
Publicado: (2022)

Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis
por: Pike, Colleen M., et al.
Publicado: (2022)

Effect of Tauroursodeoxycholic Acid on Inflammation after Ocular Alkali Burn
por: Huang, Yanqiao, et al.
Publicado: (2022)

Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats
por: Wu, Huihui, et al.
Publicado: (2020)

Osmotic Stress Induced Cell Death in Wheat Is Alleviated by Tauroursodeoxycholic Acid and Involves Endoplasmic Reticulum Stress–Related Gene Expression
por: Zhang, Liting, et al.
Publicado: (2017)

The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases
por: Vang, Sheila, et al.
Publicado: (2014)

Tauroursodeoxycholic acid: more than just a neuroprotective bile conjugate
por: Romero-Ramírez, Lorenzo, et al.
Publicado: (2017)

Metabolomics and Lipidomics Study Unveils the Impact of Tauroursodeoxycholic Acid on Hyperlipidemic Mice
por: Cui, Na, et al.
Publicado: (2023)

Tauroursodeoxycholic acid inhibits TGF-β1-induced renal fibrosis markers in cultured renal mesangial cells by regulating endoplasmic reticulum stress
por: Li, Li, et al.
Publicado: (2022)

Ursodeoxycholic Acid but Not Tauroursodeoxycholic Acid Inhibits Proliferation and Differentiation of Human Subcutaneous Adipocytes
por: Mališová, Lucia, et al.
Publicado: (2013)

Tauroursodeoxycholic acid reduces glial cell activation in an animal model of acute neuroinflammation
por: Yanguas-Casás, Natalia, et al.
Publicado: (2014)

Tauroursodeoxycholate—Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives
por: Kusaczuk, Magdalena
Publicado: (2019)

Review: The bile acids urso- and tauroursodeoxycholic acid as neuroprotective therapies in retinal disease
por: Daruich, Alejandra, et al.
Publicado: (2019)

Comparative Analysis of Urso- and Tauroursodeoxycholic Acid Neuroprotective Effects on Retinal Degeneration Models
por: Daruich, Alejandra, et al.
Publicado: (2022)

Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: The TUDCA-ALS trial protocol
por: Albanese, Alberto, et al.
Publicado: (2022)

Effects of Akt/mTOR/p70S6K Signaling Pathway Regulation on Neuron Remodeling Caused by Translocation Repair
por: Yuan, Yusong, et al.
Publicado: (2020)

Intranasal deferoxamine attenuates synapse loss via up-regulating the P38/HIF-1α pathway on the brain of APP/PS1 transgenic mice
por: Guo, Chuang, et al.
Publicado: (2015)

Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats
por: Zhuang, Kai, et al.
Publicado: (2020)

Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response
por: Hou, Yonghui, et al.
Publicado: (2021)

Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After Subarachnoid Hemorrhage in Rats
por: Wei, Boyang, et al.
Publicado: (2022)

Effects of oral tauroursodeoxycholic acid and/or intestinal probiotics on serum biochemical indexes and bile composition in patients with cholecystolithiasis
por: Gao, Fan, et al.
Publicado: (2022)

Tauroursodeoxycholic Acid Protects Retinal Pigment Epithelial Cells from Oxidative Injury and Endoplasmic Reticulum Stress In Vitro
por: Alhasani, Reem Hasaballah, et al.
Publicado: (2020)

Tauroursodeoxycholic Acid Reduces Neuroinflammation but Does Not Support Long Term Functional Recovery of Rats with Spinal Cord Injury
por: Wu, Siyu, et al.
Publicado: (2022)

Sigma-1 Receptor: A Potential Therapeutic Target for Traumatic Brain Injury
por: Shi, Mingming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rcbcjsf7vnik17ctv1ot52fpv8