Hyperosmolarity-induced AQP5 upregulation promotes inflammation and cell death via JNK1/2 Activation in human corneal epithelial cells

Tear film hyperosmolarity and anterior ocular inflammation are two clinical signs that may be indicative of dry eye disease (DED). This condition can cause pathological and functional changes to the anterior ocular surface tissues. A contributing factor may be dysfunctional aquaporin 5 (AQP5) water...

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Detalles Bibliográficos
Autores principales: Ren, Yueping, Lu, Huihui, Reinach, Peter S., Zheng, Qinxiang, Li, Jinyang, Tan, Qiufan, Zhu, Hanlei, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498491/
https://www.ncbi.nlm.nih.gov/pubmed/28680052
http://dx.doi.org/10.1038/s41598-017-05145-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498491/
https://www.ncbi.nlm.nih.gov/pubmed/28680052
http://dx.doi.org/10.1038/s41598-017-05145-y

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