Cargando…

Hyperosmolarity-induced AQP5 upregulation promotes inflammation and cell death via JNK1/2 Activation in human corneal epithelial cells

Tear film hyperosmolarity and anterior ocular inflammation are two clinical signs that may be indicative of dry eye disease (DED). This condition can cause pathological and functional changes to the anterior ocular surface tissues. A contributing factor may be dysfunctional aquaporin 5 (AQP5) water...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Yueping, Lu, Huihui, Reinach, Peter S., Zheng, Qinxiang, Li, Jinyang, Tan, Qiufan, Zhu, Hanlei, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498491/ https://www.ncbi.nlm.nih.gov/pubmed/28680052 http://dx.doi.org/10.1038/s41598-017-05145-y

Ejemplares similares

High-intensity corneal collagen crosslinking with riboflavin and UVA in rat cornea
por: Zhu, Yirui, et al.
Publicado: (2017)

Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells
por: Deng, Ruzhi, et al.
Publicado: (2015)

Altered Corneal Epithelial Dendritic Cell Morphology and Phenotype Following Acute Exposure to Hyperosmolar Saline
por: Senthil, Kirthana, et al.
Publicado: (2021)

Osmoprotectants suppress the production and activity of matrix metalloproteinases induced by hyperosmolarity in primary human corneal epithelial cells
por: Deng, Ruzhi, et al.
Publicado: (2014)

Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells
por: Li, Yanwei, et al.
Publicado: (2017)

Dynasore Protects Corneal Epithelial Cells Subjected to Hyperosmolar Stress in an In Vitro Model of Dry Eye Epitheliopathy
por: Martinez-Carrasco, Rafael, et al.
Publicado: (2023)

Origins and consequences of hyperosmolar stress in retinal pigmented epithelial cells
por: Willermain, François, et al.
Publicado: (2014)

Is inflammation a consequence of extracellular hyperosmolarity?
por: Schwartz, Laurent, et al.
Publicado: (2009)

NF-κB feedback control of JNK1 activation modulates TRPV1-induced increases in IL-6 and IL-8 release by human corneal epithelial cells
por: Wang, Z., et al.
Publicado: (2011)

Hyperosmolar Therapy for Diabetic Hyperosmolar Ketoacidosis
por: Heldeweg, Micah LA, et al.
Publicado: (2022)

DUSP5 and DUSP6 modulate corneal epithelial cell proliferation
por: Wang, Zheng, et al.
Publicado: (2010)

17-β-estradiol inhibits hyperosmolarity-induced proinflammatory cytokine elevation via the p38 MAPK pathway in human corneal epithelial cells
por: Wang, Changjun, et al.
Publicado: (2012)

Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells
por: Cavet, Megan E., et al.
Publicado: (2010)

Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells/Macrophage Co-Culture System
por: Meng, Yi-Fang, et al.
Publicado: (2021)

Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro
por: Clouzeau, Chloé, et al.
Publicado: (2012)

Dynamic Ocular Surface and Lacrimal Gland Changes Induced in Experimental Murine Dry Eye
por: Xiao, Bing, et al.
Publicado: (2015)

IGFBP-3 Mediates Metabolic Homeostasis During Hyperosmolar Stress in the Corneal Epithelium
por: Bogdan, Evan D., et al.
Publicado: (2021)

Optical Coherence Tomography Reveals Changes to Corneal Reflectivity and Thickness in Individuals with Tear Hyperosmolarity
por: Deinema, Laura Adelaide, et al.
Publicado: (2017)

Novel Cell Culture Paradigm Prolongs Mouse Corneal Epithelial Cell Proliferative Activity in vitro and in vivo
por: An, Xiaoya, et al.
Publicado: (2021)

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol
por: Jiang, Zhixin, et al.
Publicado: (2021)

Loss of Pten in Renal Tubular Cells Leads to Water Retention by Upregulating AQP2
por: Sun, Zhuo, et al.
Publicado: (2022)

L-Carnitine Suppresses Transient Receptor Potential Vanilloid Type 1 Activation in Human Corneal Epithelial Cells
por: Lucius, Alexander, et al.
Publicado: (2023)

AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M
por: Tardelli, Matteo, et al.
Publicado: (2017)

Sirt1 Regulates Corneal Epithelial Migration by Deacetylating Cortactin
por: Lin, Yong, et al.
Publicado: (2022)

Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro
por: Grauso, Marta, et al.
Publicado: (2019)

Effects of dexamethasone on C6 cell proliferation, migration and invasion through the upregulation of AQP1
por: Guan, Ying, et al.
Publicado: (2018)

Corneal Sensitivity to Hyperosmolar Eye Drops: A Novel Behavioral Assay to Assess Diabetic Peripheral Neuropathy
por: Yorek, Matthew S., et al.
Publicado: (2016)

Immunohistochemical Localization of the Aquaporins AQP1, AQP3, AQP4, and AQP5 in the Mouse Respiratory System
por: Matsuzaki, Toshiyuki, et al.
Publicado: (2009)

Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress
por: Libert, Sarah, et al.
Publicado: (2016)

Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers
por: Wright, Franklin L., et al.
Publicado: (2014)

Vitamin D Induces Global Gene Transcription in Human Corneal Epithelial Cells: Implications for Corneal Inflammation
por: Reins, Rose Y., et al.
Publicado: (2016)

BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium
por: Tiwari, Anil, et al.
Publicado: (2020)

Lacritin Salvages Human Corneal Epithelial Cells from Lipopolysaccharide Induced Cell Death
por: Vantaku, Venkat Rao, et al.
Publicado: (2015)

Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro
por: Jauhonen, Hanna-Mari, et al.
Publicado: (2011)

Hyperosmolar expansion medium improves nucleus pulposus cell phenotype
por: Laagland, Lisanne T., et al.
Publicado: (2022)

Upregulated Expression of AQP 7 in the Skeletal Muscles of Obese ob/ob Mice
por: Wakayama, Yoshihiro, et al.
Publicado: (2014)

Elliptical deep anterior lamellar keratoplasty in severe Acanthamoeba keratitis
por: Wang, Haiou, et al.
Publicado: (2023)

Unexpected localization of AQP3 and AQP4 induced by migration of primary cultured IMCD cells
por: Rose, Ralph, et al.
Publicado: (2021)

Cbl Negatively Regulates JNK Activation and Cell Death
por: Sproul, Andrew A., et al.
Publicado: (2009)

Wallenda regulates JNK-mediated cell death in Drosophila
por: Ma, X, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_u3jo4h9gb1q8o0ebrsv3lls6mg