Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours

Inhibitory interneurons in the spinal dorsal horn (SDH) are crucial for processing somatosensory information originating in the periphery. However, the effects of the acute and selective inactivation of GABAergic SDH interneurons on pain processing are not fully understood. In this study, we used de...

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Detalles Bibliográficos
Autores principales: Koga, Keisuke, Kanehisa, Kensho, Kohro, Yuta, Shiratori-Hayashi, Miho, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide, Furue, Hidemasa, Tsuda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498492/
https://www.ncbi.nlm.nih.gov/pubmed/28680103
http://dx.doi.org/10.1038/s41598-017-04972-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498492/
https://www.ncbi.nlm.nih.gov/pubmed/28680103
http://dx.doi.org/10.1038/s41598-017-04972-3

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