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Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours
Inhibitory interneurons in the spinal dorsal horn (SDH) are crucial for processing somatosensory information originating in the periphery. However, the effects of the acute and selective inactivation of GABAergic SDH interneurons on pain processing are not fully understood. In this study, we used de...
Autores principales: | Koga, Keisuke, Kanehisa, Kensho, Kohro, Yuta, Shiratori-Hayashi, Miho, Tozaki-Saitoh, Hidetoshi, Inoue, Kazuhide, Furue, Hidemasa, Tsuda, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498492/ https://www.ncbi.nlm.nih.gov/pubmed/28680103 http://dx.doi.org/10.1038/s41598-017-04972-3 |
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