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Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity

The goal of this study was to understand if exosomes derived from high-metastatic cells may influence the behavior of less aggressive cancer cells and the properties of the endothelium. We found that metastatic colon cancer cells are able to transfer their amoeboid phenotype to isogenic primary canc...

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Detalles Bibliográficos
Autores principales: Schillaci, Odessa, Fontana, Simona, Monteleone, Francesca, Taverna, Simona, Di Bella, Maria Antonietta, Di Vizio, Dolores, Alessandro, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498501/
https://www.ncbi.nlm.nih.gov/pubmed/28680152
http://dx.doi.org/10.1038/s41598-017-05002-y