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Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers

Salvia miltiorrhiza (SM) is widely used to treat microcirculatory disturbance-related diseases; its lipophilic components play important roles in this application. Cryptotanshinone (CTS), tanshinone I (TSI) and tanshinone IIA (TSA) are the most widely-studied lipophilic ingredients, but low oral bio...

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Detalles Bibliográficos
Autores principales: Xing, Lu, Tan, Zhi-Rong, Cheng, Jin-Le, Huang, Wei-Hua, Zhang, Wei, Deng, Wen, Yuan, Chun-Su, Zhou, Hong-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498502/
https://www.ncbi.nlm.nih.gov/pubmed/28680091
http://dx.doi.org/10.1038/s41598-017-02747-4