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Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers
Salvia miltiorrhiza (SM) is widely used to treat microcirculatory disturbance-related diseases; its lipophilic components play important roles in this application. Cryptotanshinone (CTS), tanshinone I (TSI) and tanshinone IIA (TSA) are the most widely-studied lipophilic ingredients, but low oral bio...
Autores principales: | Xing, Lu, Tan, Zhi-Rong, Cheng, Jin-Le, Huang, Wei-Hua, Zhang, Wei, Deng, Wen, Yuan, Chun-Su, Zhou, Hong-Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498502/ https://www.ncbi.nlm.nih.gov/pubmed/28680091 http://dx.doi.org/10.1038/s41598-017-02747-4 |
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