Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization

No licensed human vaccines are currently available against leishmaniasis. Several anti-leishmanial vaccines are currently undergoing testing, including genetically modified live-attenuated parasite vaccines. Studies with live attenuated Leishmania vaccines such as centrin deleted Leishmania donovani...

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Detalles Bibliográficos
Autores principales: Gannavaram, Sreenivas, Torcivia, John, Gasparyan, Lusine, Kaul, Amit, Ismail, Nevien, Simonyan, Vahan, Nakhasi, Hira L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498541/
https://www.ncbi.nlm.nih.gov/pubmed/28680050
http://dx.doi.org/10.1038/s41598-017-05088-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498541/
https://www.ncbi.nlm.nih.gov/pubmed/28680050
http://dx.doi.org/10.1038/s41598-017-05088-4

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