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Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization
No licensed human vaccines are currently available against leishmaniasis. Several anti-leishmanial vaccines are currently undergoing testing, including genetically modified live-attenuated parasite vaccines. Studies with live attenuated Leishmania vaccines such as centrin deleted Leishmania donovani...
Autores principales: | Gannavaram, Sreenivas, Torcivia, John, Gasparyan, Lusine, Kaul, Amit, Ismail, Nevien, Simonyan, Vahan, Nakhasi, Hira L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498541/ https://www.ncbi.nlm.nih.gov/pubmed/28680050 http://dx.doi.org/10.1038/s41598-017-05088-4 |
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