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Visualizing Temperature Mediated Activation of Gelsolin and Its Deactivation By Pip(2): A Saxs Based Study
This is the first report describing temperature based initiation of gelsolin’s F-actin depolymerization activity, even in absence of free Ca(2+) or low pH. Small angle X-ray scattering (SAXS) and circular dichroism (CD) studies revealed that temperature in the range of 30–40 °C is capable of opening...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498565/ https://www.ncbi.nlm.nih.gov/pubmed/28680082 http://dx.doi.org/10.1038/s41598-017-04975-0 |