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Synergistic cellular effects including mitochondrial destabilization, autophagy and apoptosis following low-level exposure to a mixture of lipophilic persistent organic pollutants

Humans are exposed to multiple exogenous environmental pollutants. Many of these compounds are parts of mixtures that can exacerbate harmful effects of the individual mixture components. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is primarily produced via industrial processes including incineration...

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Detalles Bibliográficos
Autores principales: Rainey, Nathan E., Saric, Ana, Leberre, Alexandre, Dewailly, Etienne, Slomianny, Christian, Vial, Guillaume, Zeliger, Harold I., Petit, Patrice X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498599/
https://www.ncbi.nlm.nih.gov/pubmed/28680151
http://dx.doi.org/10.1038/s41598-017-04654-0