Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2

PURPOSE: To study the function and expression of nine naturally occurring single-nucleotide polymorphisms (G406R, F431L, S441N, P480L, F489L, M515R, L525R, A528T and T542A) that are predicted to reside in the transmembrane regions of the ABC transporter ABCG2. METHODS: The transport activity of the...

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Detalles Bibliográficos
Autores principales: Sjöstedt, Noora, van den Heuvel, Jeroen J. M. W., Koenderink, Jan B., Kidron, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498656/
https://www.ncbi.nlm.nih.gov/pubmed/28281205
http://dx.doi.org/10.1007/s11095-017-2127-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498656/
https://www.ncbi.nlm.nih.gov/pubmed/28281205
http://dx.doi.org/10.1007/s11095-017-2127-1

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