Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP

The multi-domain transcriptional coactivators CBP/p300 integrate a multitude of signaling inputs, interacting with more than 400 proteins via one or more of their globular domains. While CBP/p300 function is typically considered in terms of these structured domains, about half of the protein consist...

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Detalles Bibliográficos
Autores principales: Contreras-Martos, Sara, Piai, Alessandro, Kosol, Simone, Varadi, Mihaly, Bekesi, Angela, Lebrun, Pierre, Volkov, Alexander N., Gevaert, Kris, Pierattelli, Roberta, Felli, Isabella C., Tompa, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498717/
https://www.ncbi.nlm.nih.gov/pubmed/28680062
http://dx.doi.org/10.1038/s41598-017-04611-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498717/
https://www.ncbi.nlm.nih.gov/pubmed/28680062
http://dx.doi.org/10.1038/s41598-017-04611-x

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