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Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP

The multi-domain transcriptional coactivators CBP/p300 integrate a multitude of signaling inputs, interacting with more than 400 proteins via one or more of their globular domains. While CBP/p300 function is typically considered in terms of these structured domains, about half of the protein consist...

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Detalles Bibliográficos
Autores principales:	Contreras-Martos, Sara, Piai, Alessandro, Kosol, Simone, Varadi, Mihaly, Bekesi, Angela, Lebrun, Pierre, Volkov, Alexander N., Gevaert, Kris, Pierattelli, Roberta, Felli, Isabella C., Tompa, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498717/ https://www.ncbi.nlm.nih.gov/pubmed/28680062 http://dx.doi.org/10.1038/s41598-017-04611-x

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