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Molecular docking analysis of nitisinone with homogentisate 1,2 dioxygenase
Alkaptonuria is an inherited disease that is caused by homogenticate accumulation. Deficiency or mutation in Homogentisate 1,2 dioxygenase gene (chromosome 3q21-q23) leads to production of incorrectly folded or truncated enzyme. Several studies indicated that competitive inhibitors of Homogentisate...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Biomedical Informatics
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498778/ https://www.ncbi.nlm.nih.gov/pubmed/28690378 http://dx.doi.org/10.6026/97320630013136 |