Cargando…

Molecular docking analysis of nitisinone with homogentisate 1,2 dioxygenase

Alkaptonuria is an inherited disease that is caused by homogenticate accumulation. Deficiency or mutation in Homogentisate 1,2 dioxygenase gene (chromosome 3q21-q23) leads to production of incorrectly folded or truncated enzyme. Several studies indicated that competitive inhibitors of Homogentisate...

Descripción completa

Detalles Bibliográficos
Autor principal: Zolfaghari, Narges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498778/
https://www.ncbi.nlm.nih.gov/pubmed/28690378
http://dx.doi.org/10.6026/97320630013136