Molecular docking based screening of Listeriolysin-O for improved inhibitors

Listeriolysine-O (LLO) is a 50KDa protein responsible for Listeria monocytogenes pathogenicity. The structure of LLO (PDB ID: 4CDB) with domains D1 to D4 is known. Therefore, it is of interest to identify conserved regions among LLO variants for destabilizing oligomerization (50 mer complex) of its...

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Detalles Bibliográficos
Autores principales: Ghafari, Sara, Komeilian, Matin, Hashemi, Mohaddese sadat, Oushani, Sareh, Rigi, Garshasb, Rashidieh, Behnam, Yarahmadi, Kamran, Khoddam, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2017
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498783/
https://www.ncbi.nlm.nih.gov/pubmed/28690383
http://dx.doi.org/10.6026/97320630013160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498783/
https://www.ncbi.nlm.nih.gov/pubmed/28690383
http://dx.doi.org/10.6026/97320630013160

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