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Relationship between Azathioprine metabolites and therapeutic efficacy in Chinese patients with neuromyelitis optica spectrum disorders

BACKGROUND: Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating autoimmune diseases in the central nervous system (CNS) that are characterized by a high relapse rate and the presence of anti-aquaporin 4 antibodies (AQP4-IgG) in the serum. Azathioprine (AZA) is a first-line immunomodula...

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Detalles Bibliográficos
Autores principales: Li, Xindi, Mei, Shenghui, Gong, Xiaoqing, Zhou, Heng, Yang, Li, Zhou, Anna, Liu, Yonghong, Li, Xingang, Zhao, Zhigang, Zhang, Xinghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498874/
https://www.ncbi.nlm.nih.gov/pubmed/28679367
http://dx.doi.org/10.1186/s12883-017-0903-5