ATM splicing variants as biomarkers for low dose dexamethasone treatment of A-T

BACKGROUND: Ataxia Telangiectasia (AT) is a rare incurable genetic disease, caused by biallelic mutations in the Ataxia Telangiectasia-Mutated (ATM) gene. Treatment with glucocorticoid analogues has been shown to improve the neurological symptoms that characterize this syndrome. Nevertheless, the mo...

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Detalles Bibliográficos
Autores principales: Menotta, Michele, Biagiotti, Sara, Spapperi, Chiara, Orazi, Sara, Rossi, Luigia, Chessa, Luciana, Leuzzi, Vincenzo, D’Agnano, Daniela, Soresina, Annarosa, Micheli, Roberto, Magnani, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498894/
https://www.ncbi.nlm.nih.gov/pubmed/28679388
http://dx.doi.org/10.1186/s13023-017-0669-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498894/
https://www.ncbi.nlm.nih.gov/pubmed/28679388
http://dx.doi.org/10.1186/s13023-017-0669-2

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