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Data normalization considerations for digital tumor dissection

In a recently published article in Genome Biology, Li and colleagues introduced TIMER, a gene expression deconvolution approach for studying tumor-infiltrating leukocytes (TILs) in 23 cancer types profiled by The Cancer Genome Atlas. Methods to characterize TIL biology are increasingly important, an...

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Detalles Bibliográficos
Autores principales: Newman, Aaron M., Gentles, Andrew J., Liu, Chih Long, Diehn, Maximilian, Alizadeh, Ash A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498978/
https://www.ncbi.nlm.nih.gov/pubmed/28679399
http://dx.doi.org/10.1186/s13059-017-1257-4