New somatic BRAF splicing mutation in Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with constitutive activation of the MAPKinase RAS-RAF-MEK-ERK cell signaling pathway. We analyzed 9 LCH cases without BRAF (V600) and MAP2K1 mutations by whole exome sequencing. We identified a new somatic BRAF splicing mutatio...

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Detalles Bibliográficos
Autores principales: Héritier, Sébastien, Hélias-Rodzewicz, Zofia, Chakraborty, Rikhia, Sengal, Amel G., Bellanné-Chantelot, Christine, Thomas, Caroline, Moreau, Anne, Fraitag, Sylvie, Allen, Carl E., Donadieu, Jean, Emile, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498996/
https://www.ncbi.nlm.nih.gov/pubmed/28679432
http://dx.doi.org/10.1186/s12943-017-0690-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498996/
https://www.ncbi.nlm.nih.gov/pubmed/28679432
http://dx.doi.org/10.1186/s12943-017-0690-z

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