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The common promoter polymorphism rs11666254 downregulates FPR2/ALX expression and increases risk of sepsis in patients with severe trauma

BACKGROUND: Formyl peptide receptor 2-lipoxin receptor (FPR2/ALX) modulates the anti-inflammatory response and therefore may be a target for treating sepsis. The purpose of this study was to investigate the association between genetic variants of the FPR2/ALX gene and sepsis after severe trauma as w...

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Detalles Bibliográficos
Autores principales: Zhang, Han, Lu, Yao, Sun, Guixiang, Teng, Fang, Luo, Nian, Jiang, Jianxin, Wen, Aiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499024/
https://www.ncbi.nlm.nih.gov/pubmed/28679406
http://dx.doi.org/10.1186/s13054-017-1757-3