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The common promoter polymorphism rs11666254 downregulates FPR2/ALX expression and increases risk of sepsis in patients with severe trauma
BACKGROUND: Formyl peptide receptor 2-lipoxin receptor (FPR2/ALX) modulates the anti-inflammatory response and therefore may be a target for treating sepsis. The purpose of this study was to investigate the association between genetic variants of the FPR2/ALX gene and sepsis after severe trauma as w...
Autores principales: | Zhang, Han, Lu, Yao, Sun, Guixiang, Teng, Fang, Luo, Nian, Jiang, Jianxin, Wen, Aiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499024/ https://www.ncbi.nlm.nih.gov/pubmed/28679406 http://dx.doi.org/10.1186/s13054-017-1757-3 |
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