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Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

BACKGROUND: In partnership with the Medicines for Malaria Venture (MMV), we screened a collection (‘Stasis Box’) of 400 compounds (which have been in clinical development but have not been approved for illnesses other than neglected infectious diseases) for inhibitory activity against Haemonchus con...

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Detalles Bibliográficos
Autores principales: Jiao, Yaqing, Preston, Sarah, Koehler, Anson V., Stroehlein, Andreas J., Chang, Bill C. H., Simpson, Kaylene J., Cowley, Karla J., Palmer, Michael J., Laleu, Benoît, Wells, Timothy N. C., Jabbar, Abdul, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499055/
https://www.ncbi.nlm.nih.gov/pubmed/28679424
http://dx.doi.org/10.1186/s13071-017-2246-x