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Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes

BACKGROUND: The RATE tool was recently developed to computationally infer the HLA restriction of given epitopes from immune response data of HLA typed subjects without additional cumbersome experimentation. RESULTS: Here, RATE was validated using experimentally defined restriction data from a set of...

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Detalles Bibliográficos
Autores principales: Paul, Sinu, Arlehamn, Cecilia S. Lindestam, Schulten, Veronique, Westernberg, Luise, Sidney, John, Peters, Bjoern, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499093/
https://www.ncbi.nlm.nih.gov/pubmed/28681704
http://dx.doi.org/10.1186/s12865-017-0204-1