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RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

Accumulation of toxic proteins in neurons has been linked with the onset of neurodegenerative diseases, which in many cases are characterized by altered neuronal function and synapse loss. Molecular chaperones help protein folding and the resolubilization of unfolded proteins, thereby reducing the p...

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Detalles Bibliográficos
Autores principales: Raut, Sandeep, Mallik, Bhagaban, Parichha, Arpan, Amrutha, Valsakumar, Sahi, Chandan, Kumar, Vimlesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499113/
https://www.ncbi.nlm.nih.gov/pubmed/28500055
http://dx.doi.org/10.1534/g3.117.041632